Biphasic Chemistry and The Solvent Case

Volume 3 - Eco-compatibility of Organic Synthesis SET Coordinated by Max Malacria

Biphasic Chemistry and The Solvent Case

Edited by

Jean-Philippe Goddard, University of Upper Alsace, France
Max Malacria, Sorbonne University, France
Cyril Ollivier , Sorbonne University, France

ISBN : 9781786305091

Publication Date : January 2020

Hardcover 230 pp

135.00 USD



Biphasic Chemistry and The Solvent Case examines recent improvements in reaction conditions, in order to affirm the role of chemistry in the sustainable field.

This book shows that those who work within the chemistry industry support limits for the use of toxic or flammable solvents, since it reduces the purifications to simple filtrations. Thanks to commercial scavengers, solid phase syntheses are now available to all. Fluorine biphasic catalysis enables extremely efficient catalyst recycling and has a high applicability potential at the industrial level.

This book also reviews the many studies that have shown that water is a solvent of choice for most synthetic reactions. Particular traits can be obtained and the effects on thermodynamics make it possible to operate at lower temperatures, thereby achieving energy savings. Finally the great diversity of application of the reactions without solvents is illustrated.


1. Solid-phase Supported Chemistry, Géraldine Gouhier.
2. Fluorous Tags and Phases for Synthesis and Catalysis, Jean-Marc Vincent.
3. Chemistry In and On Water, Marie-Christine Scherrmann.
4. Solvent-free Chemistry, Thomas-Xavier Métro, Xavier Bantreil, Jean Martinez and Frédéric Lamaty.

About the authors/editors

Jean-Philippe Goddard is Professor of Molecular Chemistry at the University of Upper Alsace, France, and Deputy Director of LIMA (Laboratory of Molecular Innovation and Applications), Strasbourg, France.

Max Malacria is Emeritus Professor at Sorbonne University, Paris, France, where his research deals with catalysis, radical chemistry and aromaticity.

Cyril Ollivier is a CNRS Research Director at the IPCM (Parisian Institute of Molecular Chemistry) at Sorbonne University.

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