Constitutional Oncogenetics

SCIENCES – Health and Society

Constitutional Oncogenetics

Noureddine Boukhatem, Mohamed I University, Morocco

ISBN : 9781789450163

Publication Date : May 2021

Hardcover 278 pp

165.00 USD



In the age of genomics, oncogenetics is a growing discipline. It is defined as the identification and management of families where there is a suspected hereditary risk of cancer. This relatively new discipline is part of a modern medicine that aims to be both preventive and predictive.

Constitutional Oncogenetics gives precise descriptions of the main syndromes that cause a predisposition for cancer. The first part examines the most common syndromes in the majority of the world, including the heightened hereditary risk of breast and ovarian cancer and Lynch syndrome. The second part introduces less common infracentesimal syndromes, such as Bloom syndrome and Fanconi syndrome.

This book is intended for oncogenetic practitioners and other specialists, as well as medical students.

“COD” Constitutional Oncogenetics Dictionary: an application on OS/Android environment available by clicking on the logo above.


Part 1. Major Syndromes
1. Hereditary Breast and Ovarian Cancer Syndrome Including Isolated Ovarian Cancers.
2. Lynch Syndrome.
3. Neurofibromatosis.
4. Familial Adenomatous Polyposis.
5. Endocrine Neoplasia.
6. Hereditary Paraganglioma–pheochromocytoma.
7. Birt–Hogg–Dubé Syndrome.
8. RASopathies.
9. Familial Malignant Melanoma.
10. Gorlin Syndrome.

Part 2. Infracentesimal Syndromes
11. Li–Fraumeni Syndrome.
12. Ataxia–telangiectasia.
13. Hyperparathyroidism.
14. Hamartomatous Polyposis Syndromes.
15. Fanconi Syndrome.
16. Hereditary Diffuse Gastric Cancer.
17. Von Hippel–Lindau Disease.
18. Xeroderma Pigmentosum.
19. Hereditary Papillary Renal Carcinoma.
20. Retinoblastoma.
21. Carney Complex.
22. Hematological Malignancies.
23. Familial Pituitary Adenomas.
24. Bloom Syndrome.
25. Werner Syndrome.

About the authors/editors

Noureddine Boukhatem is a professor at Mohamed I University, in Morocco, where he leads the Genetics and Immune Therapy team. He has also worked on the oncogenetic services of the Curie and Gustave Roussy Institute and the Jean Perrin Centre, in France.